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Mothers are Likely Sources of Children's First HPV Infection

February 2, 2021 • 3:29 pm CST
(Vax Before Cancer)

Human papillomavirus (HPV) infections are found in children, but transmission modes and outcomes are incompletely understood, commented researchers in a new study published by the U.S. CDC on January 29, 2021.

These evaluated oral samples from 331 children in Finland who participated in the Finnish Family HPV Study from birth during 9 follow-up visits (mean time 51.9 months). They tested samples for 24 HPV genotypes.

Oral HPV prevalence for children varied from 8.7% (at a 36-month visit) to 22.8% (at birth).

And 18 HPV genotypes were identified. HPV16 was the most prevalent type to persist, followed by HPV18, HPV33, and HPV6.

Persistent, oral, high-risk HPV infection for children was associated with oral HPV carriage of the mother at birth and seroconversion of the mother to high-risk HPV during follow-up (odds ratio 1.60–1.92, 95% CI 1.02–2.74).

In summary, these researchers stated, 'our results indicate that HPV infection can be acquired nonsexually and is already common at an early age. The oral cavity is the common site of the first HPV exposure, and mothers are the most likely source of first HPV infection in her child.'

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