Oesophageal Adenocarcinoma Cancer Cases Triple From Lifestyle Risk Factors
Oesophageal cancer cases have tripled in under the 50s age group over the past 30 years, a new study presented at UEG Week Virtual 2021 has found. The dramatic increases were seen in patients with oesophageal adenocarcinoma.
The research was published on October 8, 2021, conducted in the Netherlands on almost 60,000 patients, found new cases of oesophageal adenocarcinoma had risen from 0.34 to 0.92 per 100,000 population between 1989 and 2018.
There was an average increase of 1.5% in males and 3% in females.
These experts believe that the rise in cases of oesophageal adenocarcinoma reflects changes in lifestyle-related risk factors for the disease, with increases in unhealthy habits including smoking, poor diet, and reduced physical exercise.
Ali Al-Kaabi, from Radboud University Medical Centre in Nijmegen, Netherlands, and lead author of the study explained, in a press release, "The incidence of oesophageal adenocarcinoma is increasing in young adults. We know the disease is associated with Barrett's Oesophagus, which is a premalignant condition in the lower end of the esophagus."
"Gastro-oesophageal reflux (acid reflux), obesity, and smoking are also important risk factors for oesophageal adenocarcinoma."
"We also know that rates of these risk factors have all increased in young adults over the past thirty years."
Oesophageal cancer is the seventh most common cancer worldwide, and it is a highly fatal disease, accounting for 500,000 deaths each year.
Oesophageal cancer is when abnormal cells in the food pipe (esophagus) grow in an uncontrolled way. The esophagus is also known as the gullet. It is the tube that carries food from your mouth to your stomach. Most people are over the age of 60 when they are diagnosed.
There are two main subtypes; oesophageal adenocarcinoma (linked to obesity and gastro-oesophageal reflux disease) and oesophageal squamous cell carcinoma (linked to alcohol and tobacco consumption).