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How Do Immune System Cells Congregate and Communicate Against Cancer

December 14, 2021 • 7:23 pm CST
(Vax Before Cancer)

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences, wrote Bill Hathaway with YaleNews on December 9, 2021.

However, only about 20% of patients who received immune therapies designed to enhance or override natural limitations on immune system response saw sustained benefits from treatment.

Now Yale scientists have helped identify crucial ways that immune system cells congregate and communicate with each other to identify and eradicate tumors. This insight can help improve these outcomes.

Writing in the journal Cell on December 9, 2021, they report these findings might pave the way for new vaccines that may help increase survival rates in several forms of cancer.

These scientists suggest that future cancer vaccines may be more effective if they jumpstart antibody-producing B cells and helper T cells to bolster a broader immune system response.

Such vaccines could be used in conjunction with traditional immunotherapy treatments to increase survival rates of patients with several forms of cancer, the researchers said.